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UR-12947

UR-12947 is a platelet glycoprotein (GP) IIb-IIIa antagonist. UR-12947 exhibits potent inhibitory activity against platelet aggregation in human platelet-rich plasma, with an IC50 value of 3.5 nM. UR-12947 can be used in the research of arterial thrombotic diseases[1].

Product Specifications

CAS Number

718595-27-8

UNSPSC

12352005

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cardiovascular Disease

Smiles

O=S(N[C@H](C(O)=O)CNC(C1=C(C(C)C)N=C(N2CCC(C3CCNCC3)CC2)S1)=O)(C4=CC=CC=C4)=O

Molecular Formula

C26H37N5O5S2

Molecular Weight

563.73

References & Citations

[1]Scarborough RM, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43 (19) :3453-73.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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