UR-12947
UR-12947 is a platelet glycoprotein (GP) IIb-IIIa antagonist. UR-12947 exhibits potent inhibitory activity against platelet aggregation in human platelet-rich plasma, with an IC50 value of 3.5 nM. UR-12947 can be used in the research of arterial thrombotic diseases[1].
Product Specifications
CAS Number
[718595-27-8]
UNSPSC
12352005
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cardiovascular Disease
Smiles
O=S(N[C@H](C(O)=O)CNC(C1=C(C(C)C)N=C(N2CCC(C3CCNCC3)CC2)S1)=O)(C4=CC=CC=C4)=O
Molecular Formula
C26H37N5O5S2
Molecular Weight
563.73
References & Citations
[1]Scarborough RM, et al. Platelet glycoprotein IIb-IIIa antagonists as prototypical integrin blockers: novel parenteral and potential oral antithrombotic agents. J Med Chem. 2000 Sep 21;43 (19) :3453-73.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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