AT1015 (hydrochloride)
AT1015 hydrochloride is a potent antagonist of 5-HT2 receptor, with the pKi of 7.94. AT1015 inhibits vasoconstriction and blocks platelet aggregation[1].
Product Specifications
CAS Number
190508-50-0
UNSPSC
12352005
Target
5-HT Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease; Cardiovascular Disease
Smiles
O=C(C1CCN(C=O)CC1)NCCN2CC/C(CC2)=C3C4=CC=CC=C4C=CC5=CC=CC=C/35.Cl
Molecular Formula
C29H34ClN3O2
Molecular Weight
492.05
References & Citations
[1]"M Rashid, et al. Assessment of Affinity and Dissociation Ability of a Newly Synthesized 5-HT2 Antagonist, AT-1015: Comparison With Other 5-HT2 Antagonists. Comparative Study Jpn J Pharmacol. 2001 Nov;87 (3) :189-94. "
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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