Pz 285
Pz 285 is an anti-cancer agent. Pz 285 shows significant inhibitory effect on the viability of MDA-MB-231 breast cancer cells, with an IC50 of 15.0 μM. Pz 285 exhibits remarkable antitumor effects in the mouse tumor xenograft model constructed with highly lung-metastatic MDA-MB-231 LM24 Her2+ breast cancer cells. Pz 285 can be used for the study of breast cancer, especially metastatic breast cancer[1].
Product Specifications
CAS Number
[1400998-20-0]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Smiles
C[C@@]1(OC)OC2=C(/N=C3C(O[C@@](C)(OC)[C@](C)(OC)O4)=C4C(/N=C5C(O[C@@](C)(OC)[C@](C)(OC)O6)=C6/C(N/5)=N/7)=N/3)NC(/N=C8N=C7C9=C\8C(OCCO)=CC=C9OCCO)=C2O[C@@]1(C)OC
Molecular Formula
C42H50N8O16
Molecular Weight
922.89
References & Citations
[1]Kandela IK, et al. Discovery of the Antitumor Effects of a Porphyrazine Diol (Pz 285) in MDA-MB-231 Breast Tumor Xenograft Models in Mice. ACS Med Chem Lett. 2017 Jun 29;8 (7) :705-709.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103043/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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