SB 202190 (hydrochloride) (Standard)
SB 202190 (hydrochloride) (Standard) is the analytical standard of SB 202190 (hydrochloride) . This product is intended for research and analytical applications. SB 202190 hydrochloride is a selective p38 MAP kinase inhibitor with IC50s of 50 nM and 100 nM for p38α and p38β2, respectively. SB 202190 hydrochloride binds to the ATP pocket of the active recombinant human p38 kinase with a Kd of 38 nM. SB 202190 hydrochloride has anti-cancer activity[1][2]. SB202190 hydrochloride induces autophagy[3].
Product Specifications
CAS Number
350228-36-3
UNSPSC
12352005
Target
Apoptosis; Autophagy; Organoid; p38 MAPK; Reference Standards
Related Pathways
Apoptosis; Autophagy; MAPK/ERK Pathway; Others; Stem Cell/Wnt
Field of Research
Cancer; Neurological Disease
Smiles
OC1=CC=C(C2=NC(C3=CC=C(F)C=C3)=C(C4=CC=NC=C4)N2)C=C1.[H]Cl
Molecular Formula
C20H15ClFN3O
Molecular Weight
367.80
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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