Saxagliptin (hydrate) (Standard)
Saxagliptin (hydrate) (Standard) is the analytical standard of Saxagliptin (hydrate) . This product is intended for research and analytical applications. Saxagliptin hydrate (BMS-477118 hydrate) is a potent, selective, reversible, competitive and orally active dipeptidyl peptidase-4 (DPP-4) (Ki = 0.6-1.3 nM) inhibitor. Saxagliptin hydrate has the peotential for type 2 diabetes mellitus research[1][2][3].
Product Specifications
CAS Number
945667-22-1
Product Name Alternative
BMS-477118 (hydrate) (Standard)
UNSPSC
12352005
Target
Dipeptidyl Peptidase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
N[C@@H]([C@](C[C@H](C1)C2)(C[C@@H]1C3)C[C@]23O)C(N([C@@H](C4)C#N)[C@@H]5[C@H]4C5)=O.O
Molecular Formula
C18H27N3O3
Molecular Weight
333.43
References & Citations
[1]Chun-Jun Li, et al. Saxagliptin Induces β-Cell Proliferation through Increasing Stromal Cell-Derived Factor-1α In Vivo and In Vitro. Front Endocrinol (Lausanne) . 2017 Nov 27;8:326.|[2]Darshan J Dave. Saxagliptin: A dipeptidyl peptidase-4 inhibitor in the treatment of type 2 diabetes mellitus. J Pharmacol Pharmacother. 2011 Oct;2 (4) :230-5.|[3]Carolyn F Deacon, et al. Saxagliptin: a new dipeptidyl peptidase-4 inhibitor for the treatment of type 2 diabetes. Adv Ther. 2009 May;26 (5) :488-99.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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