Linagliptin-d6
Linagliptin-d6 (BI 1356-d6) is deuterium labeled Linagliptin. Linagliptin is a highly potent, selective DPP-4 inhibitor with IC50 of 1 nM.
Product Specifications
Product Name Alternative
BI 1356-d6
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C1N(C2=C(C(N1CC3=NC(C([2H])([2H])[2H])=C4C=CC=CC4=N3)=O)N(CC#CC)C(N5CCC[C@@H](N)C5)=N2)C([2H])([2H])[2H]
Molecular Formula
C25H22D6N8O2
Molecular Weight
478.58
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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