Dabigatran etexilate (Standard)

Dabigatran etexilate (Standard) is the analytical standard of Dabigatran etexilate. This product is intended for research and analytical applications. Dabigatran etexilate (BIBR 1048) is an orally active proagent of Dabigatran (a direct inhibitor of thrombin) . Dabigatran etexilate has anticoagulant effects and is used for the prophylaxis of venousthromboembolism and stroke due to atrial fibrillation[1].

Product Specifications

CAS Number

[211915-06-9]

Product Name Alternative

BIBR 1048 (Standard)

UNSPSC

12352005

Target

Reference Standards; Thrombin

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Purity

97.66

Smiles

O=C(N(C1=NC=CC=C1)CCC(OCC)=O)C2=CC=C3C(N=C(N3C)CNC4=CC=C(C(NC(OCCCCCC)=O)=N)C=C4)=C2

Molecular Formula

C34H41N7O5

Molecular Weight

627.73

References & Citations

[1]Wienen W, et al. In-vitro profile and ex-vivo anticoagulant activity of the direct thrombin inhibitor dabigatran and its orally activeprodrug, dabigatran etexilate. Thromb Haemost. 2007 Jul;98 (1) :155-62.|[2]Blair HA, Keating GM. Dabigatran Etexilate: A Review in Nonvalvular Atrial Fibrillation. Drugs. 2017;77 (3) :331-344.