A-837093 (sodium)
A-837093 sodium is a potent and orally active inhibitor of the hepatitis C virus (HCV) nonstructural protein 5B (NS5B) polymerase. A-837093 sodium shows potencies against polymerases derived from both HCV genotypes 1a (IC50 = 1.25 nM) and 1b (IC50 = 0.33 nM) . A-837093 sodium exhibits antiviral efficacy in HCV-infected chimpanzees. A-837093 sodium can be used for HCV infection research[1].
Product Specifications
CAS Number
[847440-99-7]
UNSPSC
12352005
Target
DNA/RNA Synthesis; HCV
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C1C(C(NC2=CC=C(NS(C)(=O)=O)C=C23)=NS3(=O)=O)=C(C4=CC=CC=C4[C@@]1(C)CCC(C)C)O[Na]
Molecular Formula
C24H26N3NaO6S2
Molecular Weight
539.60
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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