BMS-961955

BMS-961955 is an orally active inhibitor of HCV NS5B polymerase. BMS-961955 exhibits potent inhibitory activity against HCV genotype 1 (GT-1a/1b) replicons with EC50s of 4.3 nM and 7.9 nM, respectively. BMS-961955 can be used for the study of HCV infection[1].

Product Specifications

CAS Number

1431328-92-5

UNSPSC

12352005

Target

HCV

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

CN1CC(CC2)N(C([C@@]34CN5C(C(C=CC(F)=C6)=C6[C@]3([H])C4)=C(C7CCCCC7)C8=C5C=C(C(NS(=O)(C9(C)CC9)=O)=O)C=C8)=O)C2C1

Molecular Formula

C37H43FN4O4S

Molecular Weight

658.83

References & Citations

[1]Zheng BZ, et al. Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett. 2017 Aug 1;27 (15) :3294-3300.