BMS-961955
BMS-961955 is an orally active inhibitor of HCV NS5B polymerase. BMS-961955 exhibits potent inhibitory activity against HCV genotype 1 (GT-1a/1b) replicons with EC50s of 4.3 nM and 7.9 nM, respectively. BMS-961955 can be used for the study of HCV infection[1].
Product Specifications
CAS Number
1431328-92-5
UNSPSC
12352005
Target
HCV
Related Pathways
Anti-infection
Applications
COVID-19-anti-virus
Field of Research
Infection
Smiles
CN1CC(CC2)N(C([C@@]34CN5C(C(C=CC(F)=C6)=C6[C@]3([H])C4)=C(C7CCCCC7)C8=C5C=C(C(NS(=O)(C9(C)CC9)=O)=O)C=C8)=O)C2C1
Molecular Formula
C37H43FN4O4S
Molecular Weight
658.83
References & Citations
[1]Zheng BZ, et al. Discovery of BMS-961955, an allosteric inhibitor of the hepatitis C virus NS5B polymerase. Bioorg Med Chem Lett. 2017 Aug 1;27 (15) :3294-3300.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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