Tandutinib (Standard)
Tandutinib (Standard) is the analytical standard of Tandutinib. This product is intended for research and analytical applications. Tandutinib (MLN518) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib can be used for acute myelogenous leukemia (AML) [1][2]. Tandutinib has the ability to cross the blood-brain barrier[3].
Product Specifications
Product Name Alternative
MLN518 (Standard) ; CT53518 (Standard)
UNSPSC
12352005
Target
Apoptosis; c-Kit; FLT3; PDGFR; Reference Standards
Related Pathways
Apoptosis; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5
Molecular Formula
C31H42N6O4
Molecular Weight
562.70
References & Citations
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-10202R/
Scientific Category
Reference Standards
CAS Number
[387867-13-2]
Available Sizes
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