Tandutinib (hydrochloride) (Standard)
Tandutinib (hydrochloride) (Standard) is the analytical standard of Tandutinib (hydrochloride) . This product is intended for research and analytical applications. Tandutinib hydrochloride (MLN518 hydrochloride) is a potent and selective inhibitor of the FLT3 with an IC50 of 0.22 μM, and also inhibits c-Kit and PDGFR with IC50s of 0.17 μM and 0.20 μM, respectively. Tandutinib hydrochloride can be used for acute myelogenous leukemia (AML) [1][2]. Tandutinib hydrochloride has the ability to cross the blood-brain barrier[3].
Product Specifications
CAS Number
2438900-70-8
Product Name Alternative
MLN518 (hydrochloride) (Standard) ; CT53518 (hydrochloride) (Standard)
UNSPSC
12352005
Target
Apoptosis; c-Kit; FLT3; PDGFR; Reference Standards
Related Pathways
Apoptosis; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(N1CCN(C2=C(C(C=C3OCCCN4CCCCC4)=NC=N2)C=C3OC)CC1)NC5=CC=C(OC(C)C)C=C5.Cl
Molecular Formula
C31H43ClN6O4
Molecular Weight
599.16
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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