BMS-309403 (sodium) (Standard)
BMS-309403 (sodium) (Standard) is the analytical standard of BMS-309403 (sodium) . This product is intended for research and analytical applications. BMS-309403 sodium is a potent, orally active, and selective adipocyte fatty acid binding protein (also known as FABP4, aP2) inhibitor, with Kis of [1][2][3].
Product Specifications
CAS Number
2802523-05-1
UNSPSC
12352005
Target
FABP; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease; Cardiovascular Disease
Smiles
O=C(O[Na])COC1=CC(C2=CC=CC=C2N3N=C(C4=CC=CC=C4)C(C5=CC=CC=C5)=C3CC)=CC=C1
Molecular Formula
C31H25N2NaO3
Molecular Weight
496.53
References & Citations
[1]Sulsky R, et al. Potent and selective biphenyl azole inhibitors of adipocyte fatty acid binding protein (aFABP) . Bioorg Med Chem Lett. 2007;17 (12) :3511-3515.|[2]Lin W, et al. BMS309403 stimulates glucose uptake in myotubes through activation of AMP-activated protein kinase. PLoS One. 2012;7 (8) :e44570.|[3]Lee MY, et al. Chronic administration of BMS309403 improves endothelial function in apolipoprotein E-deficient mice and in cultured human endothelial cells. Br J Pharmacol. 2011;162 (7) :1564-1576.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
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