NC-2100
NC-2100 is a PPAR activator. NC-2100 can effectively reduce the plasma glucose and triglyceride levels of obese KKAy mice. NC-2100 can induce UCP1 and UCP2 expression in mesenteric and subcutaneous WAT of mice. NC-2100 can be used in research related to type 2 diabetes[1].
Product Specifications
CAS Number
179068-64-5
UNSPSC
12352005
Target
PPAR
Related Pathways
Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Field of Research
Metabolic Disease
Smiles
O=C(N1)SC(CC2=CC3=CC=C(OCC4=CC=CC=C4)C=C3N=C2)C1=O
Molecular Formula
C20H16N2O3S
Molecular Weight
364.42
References & Citations
[1]Fukui Y, et al. A new thiazolidinedione, NC-2100, which is a weak PPAR-gamma activator, exhibits potent antidiabetic effects and induces uncoupling protein 1 in white adipose tissue of KKAy obese mice. Diabetes. 2000 May;49 (5) :759-67.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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