Dasatinib (hydrochloride) (Standard)
Dasatinib (hydrochloride) (Standard) is the analytical standard of Dasatinib (hydrochloride) . This product is intended for research and analytical applications. Dasatinib (BMS-354825) hydrochloride is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Kis are 16 pM and 30 pM for Src and Bcr-Abl, respectively. Dasatinib hydrochloride inhibits Bcr-Abl and Src with IC50s of [1]. Dasatinib hydrochloride also induces apoptosis and autophagy.
Product Specifications
CAS Number
854001-07-3
Product Name Alternative
BMS-354825 (hydrochloride) (Standard)
UNSPSC
12352005
Target
Apoptosis; Autophagy; Bcr-Abl; Reference Standards; Src
Related Pathways
Apoptosis; Autophagy; Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=CN=C(S1)NC2=NC(C)=NC(N3CCN(CC3)CCO)=C2)NC4=C(C=CC=C4Cl)C.[H]Cl
Molecular Formula
C22H27Cl2N7O2S
Molecular Weight
524.47
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Available Sizes
Frequently Asked Questions
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