Melinamide (Standard)

Melinamide (Standard) is the analytical standard of Melinamide. This product is intended for research and analytical applications. Melinamide, an amide derivative of an unsaturated long-chain fatty acid, is an inhibitor of cholesterol absorption with an IC50 of 20.9 μM.

Product Specifications

CAS Number

[14417-88-0]

Product Name Alternative

AC 223 (Standard) ; DL-N- (α-Methylbenzyl) linoleamide (Standard)

UNSPSC

12352005

Target

Acyltransferase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

CCCCC/C=C\C/C=C\CCCCCCCC(NC(C1=CC=CC=C1)C)=O

Molecular Formula

C26H41NO

Molecular Weight

383.61

References & Citations

[1]Kusunoki J, et al. Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells Nihon Yakurigaku Zasshi. 1997 Dec;110 (6) :357-65.|[2]Natori K, et al. Mechanism of the inhibition of cholesterol absorption by DL-melinamide: inhibition of cholesterol esterification. Jpn J Pharmacol. 1986 Dec;42 (4) :517-23.|[3]Matsubara K, et al. Cholesterol-lowering effect of N- (alpha-methylbenzyl) linoleamide (melinamide) in cholesterol-fed diabetic rats. Atherosclerosis. 1988 Aug;72 (2-3) :199-204.