Senazodan (hydrochloride) (Standard)

Senazodan (hydrochloride) (Standard) is the analytical standard of Senazodan (hydrochloride) (HY-101693A) . This product is intended for research and analytical applications. Senazodan (MCI 154) (hydrochloride), as a Ca2+ sensitiser, shows inhibition effect on PDE III[1][2].

Product Specifications

CAS Number

[98326-33-1]

Target

Phosphodiesterase (PDE) ; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Smiles

[H]Cl.O=C1CCC(C2=CC=C(NC3=CC=NC=C3)C=C2)=NN1

Molecular Formula

C15H15ClN4O

Molecular Weight

302.76

References & Citations

[1]Lehtonen LA, et al. Pharmacokinetics and pharmacodynamics of intravenous inotropic agents. Clin Pharmacokinet. 2004;43 (3) :187-203.|[2]Erhardt L. An emerging role for calcium sensitisation in the treatment of heart failure. Expert Opin Investig Drugs. 2005 Jun;14 (6) :659-70.|[3]Yang G, et al. Effects of MCI-154 on vascular reactivity and its mechanisms after hemorrhagic shock in rats. J Cardiovasc Pharmacol. 2006;47 (6) :751-757.|[4]Ming MJ, et al. Effects of MCI-154, a calcium sensitizer, on cardiac dysfunction in endotoxic shock in rabbits. Shock. 2000;13 (6) :459-463.