YM-58790 (Standard)

YM-58790 (Standard) is the analytical standard of YM-58790 (HY-101679) . This product is intended for research and analytical applications. YM-58790 is a potent antagonist of mAChR. YM-58790 binds M1, M2, M3 with Ki values of 28 nM, 260 nM, and 15 nM. YM-58790 exhibits potent inhibitory activity on bladder pressuer in reflexly-evoked rhythmic contraction in rats[1].

Product Specifications

CAS Number

[214558-72-2]

Target

MAChR; Reference Standards

Related Pathways

GPCR/G Protein; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

O=C(OC1CCN(CC2=CC=C(NC)C=C2)CC1)NC(C3=CC=CC=C3)C4=CC=CC=C4.[H]Cl

Molecular Formula

C27H32ClN3O2

Molecular Weight

466.01

References & Citations

[1]Naito R, et al. Selective muscarinic antagonists. I. Synthesis and antimuscarinic properties of 4-piperidyl benzhydrylcarbamate derivatives. Chem Pharm Bull (Tokyo) . 1998 Aug;46 (8) :1274-85.