LTURM34 (Standard)
LTURM34 (Standard) is the analytical standard of LTURM34 (HY-101667) . This product is intended for research and analytical applications. LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM) . LTURM34 exhibits 170-fold selectivity for DNA-PK over PI3K. LTURM34 shows potent antiproliferative activity in a wide range of tumor cell lines[1].
Product Specifications
CAS Number
[1879887-96-3]
Target
DNA-PK; Reference Standards
Related Pathways
Cell Cycle/DNA Damage; Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C1C2=CC=CC(C3=CC=CC4=C3SC5=C4C=CC=C5)=C2OC(N6CCOCC6)=N1
Molecular Formula
C24H18N2O3S
Molecular Weight
414.48
References & Citations
[1]Morrison R, et al. Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur J Med Chem. 2016 Mar 3;110:326-39.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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