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MSC2530818 (Standard)

MSC2530818 (Standard) is the analytical standard of MSC2530818. This product is intended for research and analytical applications. MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8.

Product Specifications

CAS Number

1883423-59-3

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

CDK

Related Pathways

Cell Cycle/DNA Damage

Field of Research

Cancer

Purity

99.16

Smiles

O=C(N1[C@H](C2=CC=C(Cl)C=C2)CCC1)C3=CN=C(NN=C4C)C4=C3

Molecular Formula

C18H17ClN4O

Molecular Weight

340.81

Precautions

H302, H315, H319, H335

References & Citations

[1]Czodrowski P, et al. Structure-Based Optimization of Potent, Selective, and Orally Bioavailable CDK8 Inhibitors Discovered by High-Throughput Screening. J Med Chem. 2016 Oct 27;59 (20) :9337-9349.

Shipping Conditions

Blue Ice

Storage Conditions

4°C, sealed storage, away from light and moisture

Scientific Category

Reference Standards

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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