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RP 70676 (Standard)

RP 70676 (Standard) is the analytical standard of RP 70676 (HY-101576) . This product is intended for research and analytical applications. RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT.

Product Specifications

CAS Number

[136609-26-2]

Target

Acyltransferase; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

CC1=CC(C)=NN1CCCCCSC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2

Molecular Formula

C25H28N4S

Molecular Weight

416.58

References & Citations

[1]M.J. Ashton, et al. RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT) . Bioorganic & Medicinal Chemistry Letters Volume 2, Issue 5, 1992, Pages 375-380.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

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