RP 70676 (Standard)
RP 70676 (Standard) is the analytical standard of RP 70676 (HY-101576) . This product is intended for research and analytical applications. RP 70676 is a potent inhibitor of ACAT, with IC50 of 25 and 44 nM for rat and rabbit ACAT.
Product Specifications
CAS Number
[136609-26-2]
Target
Acyltransferase; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
CC1=CC(C)=NN1CCCCCSC2=NC(C3=CC=CC=C3)=C(C4=CC=CC=C4)N2
Molecular Formula
C25H28N4S
Molecular Weight
416.58
References & Citations
[1]M.J. Ashton, et al. RP 70676: A potent systematically available inhibitor of acyl-CoA:cholesterol O-acyl transferase (ACAT) . Bioorganic & Medicinal Chemistry Letters Volume 2, Issue 5, 1992, Pages 375-380.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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