Imanixil (Standard)
Imanixil (Standard) is the analytical standard of Imanixil. This product is intended for research and analytical applications. Imanixil (HOE-402 free base) is an orally active LDL receptor (LDLR) inducer. Imanixil can reduce cholesterol levels by inhibiting VLDL-lipid production. Imanixil can delay atherosclerosis profession. Imanixil can be used for the research of cardiovascular disease, such as atherosclerosis[1].
Product Specifications
CAS Number
75689-93-9
Target
LDLR; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C(C1=CN=C(N2CC(C)(C)NC2=O)N=C1N)NC3=CC=CC(C(F)(F)F)=C3
Molecular Formula
C17H17F3N6O2
Molecular Weight
394.35
References & Citations
[1]Draijer R, et al. HOE 402 lowers serum cholesterol levels by reducing VLDL-lipid production, and not by induction of the LDL receptor, and reduces atherosclerosis in wild-type and LDL receptor-deficient mice. Biochem Pharmacol. 2002 May 1;63 (9) :1755-61.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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