IDRA 21 (Standard)

IDRA 21 (Standard) is the analytical standard of IDRA 21 (HY-101528) . This product is intended for research and analytical applications. IDRA 21 is a positive and orally active modulator of the AMPA receptor. IDRA 21 facilitates excitatory neurotransmission via GluR1/2 receptors. IDRA 21 has the potential for the research of cognitive/memory disorders, including those associated with aging[1].

Product Specifications

CAS Number

[22503-72-6]

Target

IGluR; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling; Others

Field of Research

Neurological Disease

Smiles

CC(NC1=CC=C(Cl)C=C12)NS2(=O)=O

Molecular Formula

C8H9ClN2O2S

Molecular Weight

232.69

References & Citations

[1]Buccafusco JJ, et al. The effects of IDRA 21, a positive modulator of the AMPA receptor, on delayed matching performance by young and aged rhesus monkeys. Neuropharmacology. 2004 Jan;46 (1) :10-22. doi: 10.1016/j.neuropharm.2003.07.002.|[2]Yamada KA, et al. The diazoxide derivative IDRA 21 enhances ischemic hippocampal neuron injury. Ann Neurol. 1998 May;43 (5) :664-9.