TC13172 (Standard)
TC13172 (Standard) is the analytical standard of TC13172 (HY-101524) . This product is intended for research and analytical applications. TC13172 is a mixed lineage kinase domain-like protein (MLKL) inhibitor with an EC50 value of 2 nM for HT-29 cells[1].
Product Specifications
CAS Number
[2093393-05-4]
Target
Mixed Lineage Kinase; Reference Standards
Related Pathways
MAPK/ERK Pathway; Others
Field of Research
Cancer
Smiles
O=C1C2=C(N=C(S(C)(=O)=O)N2C)N(CC#CC3=CC(O)=CC=C3)C(N1C)=O
Molecular Formula
C17H16N4O5S
Molecular Weight
388.40
References & Citations
[1]Bo Yan, et al. Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein.ChemCommun (Camb) . 2017 Mar 28;53 (26) :3637-3640.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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