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Cdc7-IN-1 (Standard)

Cdc7-IN-1 (Standard) is the analytical standard of Cdc7-IN-1. This product is intended for research and analytical applications. Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1].

Product Specifications

CAS Number

1402055-25-7

Target

CDK; Reference Standards

Related Pathways

Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

O=C1C(C(OCC)=O)=C(NC2=C(Cl)C=CC=C2)O/C1=C\C3=CNC4=C3C=CC=N4

Molecular Formula

C21H16ClN3O4

Molecular Weight

409.82

References & Citations

[1]Irie T, et al. Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors. Eur J Med Chem. 2017 Apr 21;130:406-418.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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