MELK-IN-1 (Standard)
MELK-IN-1 (Standard) is the analytical standard of MELK-IN-1. This product is intended for research and analytical applications. MELK-IN-1 is a potent inhibitor of maternal embryonic leucine zipper kinase (MELK) with an IC50 and a Ki of 3 nM and 0.39 nM, respectively.
Product Specifications
CAS Number
2095596-44-2
Target
MELK; Reference Standards
Related Pathways
Others; PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C(C1=CC2=C(NC(/C2=C(NC3=CC=C(N(C)C(CN4CCN(C)CC4)=O)C=C3)/C5=CC=CC=C5)=O)C=C1)OC
Molecular Formula
C31H33N5O4
Molecular Weight
539.62
References & Citations
[1]Edupuganti R, et al. Discovery of a potent inhibitor of MELK that inhibits expression of the anti-apoptotic protein Mcl-1 and TNBC cell growth. Bioorg Med Chem. 2017 May 1;25 (9) :2609-2616.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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