SB290157 (trifluoroacetate) (Standard)

SB290157 (trifluoroacetate) (Standard) is the analytical standard of SB290157 (trifluoroacetate) (HY-101502A) . This product is intended for research and analytical applications. SB290157 trifluoroacetate is a potent and selective C3a receptor antagonist with an IC50 of 200 nM.

Product Specifications

CAS Number

[1140525-25-2]

Target

Complement System; Reference Standards

Related Pathways

Immunology/Inflammation; Others

Field of Research

Inflammation/Immunology

Smiles

N=C(N)NCCC[C@@H](C(O)=O)NC(COCC(C1=CC=CC=C1)C2=CC=CC=C2)=O.OC(C(F)(F)F)=O

Molecular Formula

C24H29F3N4O6

Molecular Weight

526.51

References & Citations

[1]Ames RS, et al. Identification of a selective nonpeptide antagonist of the anaphylatoxin C3areceptor that demonstrates antiinflammatory activity in animal models. J Immunol. 2001 May 15;166 (10) :6341-8.|[2]Hutamekalin P, et al. Effect of the C3a-receptor antagonist SB 290157 on anti-OVA polyclonalantibody-induced arthritis. J Pharmacol Sci. 2010;112 (1) :56-63.