SB290157 (trifluoroacetate) (Standard)
SB290157 (trifluoroacetate) (Standard) is the analytical standard of SB290157 (trifluoroacetate). This product is intended for research and analytical applications. SB290157 trifluoroacetate is a potent and selective C3a receptor antagonist with an IC50 of 200 nM.
Product Specifications
CAS Number
1140525-25-2
Target
Complement System; Reference Standards
Related Pathways
Immunology/Inflammation; Others
Field of Research
Inflammation/Immunology
Smiles
N=C(N)NCCC[C@@H](C(O)=O)NC(COCC(C1=CC=CC=C1)C2=CC=CC=C2)=O.OC(C(F)(F)F)=O
Molecular Formula
C24H29F3N4O6
Molecular Weight
526.51
References & Citations
[1]Ames RS, et al. Identification of a selective nonpeptide antagonist of the anaphylatoxin C3areceptor that demonstrates antiinflammatory activity in animal models. J Immunol. 2001 May 15;166 (10) :6341-8.|[2]Hutamekalin P, et al. Effect of the C3a-receptor antagonist SB 290157 on anti-OVA polyclonalantibody-induced arthritis. J Pharmacol Sci. 2010;112 (1) :56-63.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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