SR-18292 (Standard)
SR-18292 (Standard) is the analytical standard of SR-18292 (HY-101491) . This product is intended for research and analytical applications. SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.
Product Specifications
CAS Number
[2095432-55-4]
Target
Autophagy; PGC-1α; Reference Standards
Related Pathways
Autophagy; Metabolic Enzyme/Protease; Others
Field of Research
Metabolic Disease
Smiles
CC1=CC=C(CN(C(C)(C)C)CC(O)COC2=CC=CC3=C2C=CN3)C=C1
Molecular Formula
C23H30N2O2
Molecular Weight
366.50
References & Citations
[1]Sharabi K, et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23;169 (1) :148-160.e15.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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