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SR-18292 (Standard)

SR-18292 (Standard) is the analytical standard of SR-18292. This product is intended for research and analytical applications. SR-18292 is a PPAR gamma coactivator-1α (PGC-1α) inhibitor, which increases PGC-1α acetylation, suppresses gluconeogenic gene expression and reduces glucose production in hepatocytes.

Product Specifications

CAS Number

2095432-55-4

Target

Autophagy; PGC-1α; Reference Standards

Related Pathways

Autophagy; Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

CC1=CC=C(CN(C(C)(C)C)CC(O)COC2=CC=CC3=C2C=CN3)C=C1

Molecular Formula

C23H30N2O2

Molecular Weight

366.50

References & Citations

[1]Sharabi K, et al. Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes. Cell. 2017 Mar 23;169 (1) :148-160.e15.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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