CC-885 (Standard)
CC-885 (Standard) is the analytical standard of CC-885. This product is intended for research and analytical applications. CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation.
Product Specifications
CAS Number
1010100-07-8
Target
Ligands for E3 Ligase; Molecular Glues; Reference Standards
Related Pathways
Others; PROTAC
Field of Research
Cancer
Smiles
O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
Molecular Formula
C22H21ClN4O4
Molecular Weight
440.88
References & Citations
[1]Mary E. Matyskiela, et al. A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature. 2016 Jul 14;535 (7611) :252-7.|[2]Jochem M, et al. Degradome analysis to identify direct protein substrates of small-molecule degraders[J]. bioRxiv, 2024: 2024.01. 28.577572.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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