CC-885 (Standard)

CC-885 (Standard) is the analytical standard of CC-885 (HY-101488) . This product is intended for research and analytical applications. CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation.

Product Specifications

CAS Number

[1010100-07-8]

Target

Ligands for E3 Ligase; Molecular Glues; Reference Standards

Related Pathways

Others; PROTAC

Field of Research

Cancer

Smiles

O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4

Molecular Formula

C22H21ClN4O4

Molecular Weight

440.88

References & Citations

[1]Mary E. Matyskiela, et al. A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase. Nature. 2016 Jul 14;535 (7611) :252-7.|[2]Jochem M, et al. Degradome analysis to identify direct protein substrates of small-molecule degraders[J]. bioRxiv, 2024: 2024.01. 28.577572.