LF3 (Standard)
LF3 (Standard) is the analytical standard of LF3 (HY-101486) . This product is intended for research and analytical applications. LF3 is an antagonist of the β-Catenin/TCF4 interaction with antitumor activity; has an IC50 of 1.65 μM[1].
Product Specifications
CAS Number
[664969-54-4]
Target
Reference Standards; β-catenin
Related Pathways
Others; Stem Cell/Wnt
Field of Research
Cancer
Smiles
S=C(N1CCN(C/C=C/C2=CC=CC=C2)CC1)NC3=CC=C(S(=O)(N)=O)C=C3
Molecular Formula
C20H24N4O2S2
Molecular Weight
416.56
References & Citations
[1]Fang L, et al. A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. Cancer Res. 2016 Feb 15;76 (4) :891-901.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101486R/
Scientific Category
Reference Standards
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