LF3 (Standard)

LF3 (Standard) is the analytical standard of LF3 (HY-101486) . This product is intended for research and analytical applications. LF3 is an antagonist of the β-Catenin/TCF4 interaction with antitumor activity; has an IC50 of 1.65 μM[1].

Product Specifications

CAS Number

[664969-54-4]

Target

Reference Standards; β-catenin

Related Pathways

Others; Stem Cell/Wnt

Field of Research

Cancer

Smiles

S=C(N1CCN(C/C=C/C2=CC=CC=C2)CC1)NC3=CC=C(S(=O)(N)=O)C=C3

Molecular Formula

C20H24N4O2S2

Molecular Weight

416.56

References & Citations

[1]Fang L, et al. A Small-Molecule Antagonist of the β-Catenin/TCF4 Interaction Blocks the Self-Renewal of Cancer Stem Cells and Suppresses Tumorigenesis. Cancer Res. 2016 Feb 15;76 (4) :891-901.