Dihydromunduletone (Standard)
Dihydromunduletone (Standard) is the analytical standard of Dihydromunduletone (HY-101483) . This product is intended for research and analytical applications. Dihydromunduletone (DHM) is a rotenoid derivative and a selective, potent adhesion G protein-coupled receptor (aGPCR) (GPR56 and GPR114/ADGRG5) antagonist with an IC 50 of 20.9 μM for GPR56, but not inhibit GPR110 or class A GPCRs[1].
Product Specifications
CAS Number
[674786-20-0]
Target
Drug Derivative; Orphan Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Others
Field of Research
Cancer; Neurological Disease
Smiles
CC1(C)C=CC2=C(OC)C(CC(C3=C(O)C=C4C(CC(O)C(C)(C)O4)=C3)=O)=CC=C2O1
Molecular Formula
C25H28O6
Molecular Weight
424.49
References & Citations
[1]Hannah M. Stoveken, et al. Dihydromunduletone Is a Small-Molecule Selective Adhesion G Protein–Coupled Receptor Antagonist. Mol Pharmacol. 2016 Sep; 90 (3) : 214–224.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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