Fenobam (Standard)
Fenobam (Standard) is the analytical standard of Fenobam. This product is intended for research and analytical applications. Fenobam is a selective and orally active mGluR5 antagonist (IC50=84 nM) that can penetrate the blood-brain barrier. Fenobam shows the Kd values of 54 nM and 31 nM on rat and human recombinant mGlu5 receptors, respectively. Fenobam has anxiolytic activity, inhibits self-administration behavior in mice, and induces apoptosis in cancer cells. Fenobam can be used for research on neurological diseases, cancer and drug addiction[1][2][3].
Product Specifications
CAS Number
57653-26-6
UNSPSC
12352005
Target
Apoptosis; mGluR; Reference Standards
Related Pathways
Apoptosis; GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Cancer; Neurological Disease
Smiles
O=C(NC1=NC(CN1C)=O)NC2=CC=CC(Cl)=C2
Molecular Formula
C11H11ClN4O2
Molecular Weight
266.69
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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