(±) -Zanubrutinib (Standard)
(±) -Zanubrutinib (Standard) is the analytical standard of (±) -Zanubrutinib (HY-101474) . This product is intended for research and analytical applications. (±) -Zanubrutinib ((±) -BGB-3111) is the racemate of Zanubrutinib (HY-101474A) . (±) -Zanubrutinib inhibits Bruton's tyrosine kinase (Btk) with an IC50 of 0.63 nM[1].
Product Specifications
CAS Number
[1633350-06-7]
Target
Btk; Reference Standards
Related Pathways
Others; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
NC(C1=C2N(N=C1C3=CC=C(OC4=CC=CC=C4)C=C3)C(C5CCN(C(C=C)=O)CC5)CCN2)=O
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
References & Citations
[1]Na L, et al. BGB-3111 is a novel and highly selective Bruton's tyrosine kinase (BTK) inhibitor. [abstract]. In: Proceedings of the 106th Annual Meeting of the American Association for Cancer Research; 2015 Apr 18-22; Philadelphia, PA. Philadelphia (PA) : AACR; Cancer Res 2015;75 (15 Suppl) :Abstract nr 2597. doi:10.1158/1538-7445.AM2015-2597
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Curated Selection
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