EMD527040 (hydrochloride)
EMD527040 (hydrochloride) is a highly potent and selective αvβ6 antagonist with anti-fibrotic activity. EMD527040 (hydrochloride) is used in the research of liver cancer and liver fibrosis[1].
Product Specifications
UNSPSC
12352005
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cancer
Smiles
O=C(O)CC(NC([C@@H](NC(CCCCNC1=NC=CC=C1)=O)COCC2=CC=CC=C2)=O)C3=CC(Cl)=CC(Cl)=C3.Cl
Molecular Formula
C29H33Cl3N4O5
Molecular Weight
623.96
References & Citations
[1]Patsenker E, et al. Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression. Gastroenterology. 2008 Aug;135 (2) :660-70.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-101473A/
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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