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EMD527040 (hydrochloride)

EMD527040 (hydrochloride) is a highly potent and selective αvβ6 antagonist with anti-fibrotic activity. EMD527040 (hydrochloride) is used in the research of liver cancer and liver fibrosis[1].

Product Specifications

UNSPSC

12352005

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cancer

Smiles

O=C(O)CC(NC([C@@H](NC(CCCCNC1=NC=CC=C1)=O)COCC2=CC=CC=C2)=O)C3=CC(Cl)=CC(Cl)=C3.Cl

Molecular Formula

C29H33Cl3N4O5

Molecular Weight

623.96

References & Citations

[1]Patsenker E, et al. Inhibition of integrin alphavbeta6 on cholangiocytes blocks transforming growth factor-beta activation and retards biliary fibrosis progression. Gastroenterology. 2008 Aug;135 (2) :660-70.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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