RAD51 Inhibitor B02 (Standard)
RAD51 Inhibitor B02 (Standard) is the analytical standard of RAD51 Inhibitor B02. This product is intended for research and analytical applications. RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.
Product Specifications
CAS Number
1290541-46-6
Target
Apoptosis; RAD51; Reference Standards
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Others
Field of Research
Cancer
Smiles
O=C1N(CC2=CC=CC=C2)C(/C=C/C3=CC=CN=C3)=NC4=C1C=CC=C4
Molecular Formula
C22H17N3O
Molecular Weight
339.39
References & Citations
[1]Huang F, et al. Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening. ACS Chem Biol. 2011 Jun 17;6 (6) :628-35.|[2]Huang F, et al. A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts. PLoS One. 2014 Jun 27;9 (6) :e100993.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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