RAD51 Inhibitor B02 (Standard)

RAD51 Inhibitor B02 (Standard) is the analytical standard of RAD51 Inhibitor B02 (HY-101462) . This product is intended for research and analytical applications. RAD51 Inhibitor B02 (B02) is an inhibitor of human RAD51 with an IC50 of 27.4 μM.

Product Specifications

CAS Number

[1290541-46-6]

Target

Apoptosis; RAD51; Reference Standards

Related Pathways

Apoptosis; Cell Cycle/DNA Damage; Others

Field of Research

Cancer

Smiles

O=C1N(CC2=CC=CC=C2)C(/C=C/C3=CC=CN=C3)=NC4=C1C=CC=C4

Molecular Formula

C22H17N3O

Molecular Weight

339.39

References & Citations

[1]Huang F, et al. Identification of specific inhibitors of human RAD51 recombinase using high-throughput screening. ACS Chem Biol. 2011 Jun 17;6 (6) :628-35.|[2]Huang F, et al. A small molecule inhibitor of human RAD51 potentiates breast cancer cell killing by therapeutic agents in mouse xenografts. PLoS One. 2014 Jun 27;9 (6) :e100993.