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JZP-430 (Standard)

JZP-430 (Standard) is the analytical standard of JZP-430 (HY-101457) . This product is intended for research and analytical applications. JZP-430 is a potent, highly selective, irreversible inhibitor of α/β-hydrolase domain 6 (ABHD6) with an IC50 of 44 nM, exhibits ~230-fold selectivity over fatty acid amide hydrolase (FAAH) and lysosomal acid lipase (LAL) [1].

Product Specifications

CAS Number

[1672691-74-5]

Target

MAGL; Reference Standards

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

O=C(OC1=NSN=C1N2CCOCC2)N(C3CCCCCCC3)C

Molecular Formula

C16H26N4O3S

Molecular Weight

354.47

References & Citations

[1]Patel JZ, et al. Optimization of 1,2,5-thiadiazole carbamates as potent and selective ABHD6 inhibitors. ChemMedChem. 2015 Feb;10 (2) :253-65.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Curated Selection

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