PCPA methyl ester (hydrochloride) (Standard)
PCPA methyl ester (hydrochloride) (Standard) is the analytical standard of PCPA methyl ester (hydrochloride). This product is intended for research and analytical applications. PCPA methyl ester hydrochloride (4-Chloro-DL-phenylalanine methyl ester hydrochloride), a reversible tryptophan hydroxylase inhibitor, is a serotonin (5-HT) synthesis inhibitor. PCPA methyl ester hydrochloride crosses the blood brain barrier and reduces 5-HT central availability[1][2].
Product Specifications
CAS Number
14173-40-1
Target
5-HT Receptor; Reference Standards; Tryptophan Hydroxylase
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
NC(CC1=CC=C(Cl)C=C1)C(OC)=O.Cl
Molecular Formula
C10H13Cl2NO2
Molecular Weight
250.13
References & Citations
[1]Dool-Ri Oh, et al. Sedative and hypnotic effects of Vaccinium bracteatum Thunb. through the regulation of serotonegic and GABA A-ergic systems: Involvement of 5-HT 1A receptor agonistic activity. Biomed Pharmacother. 2019 Jan;109:2218-2227.|[2]Fabio Bellia, et al. Transient serotonin depletion at adolescence, but not at early infancy, reduced subsequent anxiety-like behavior and alcohol intake in female mice. Psychopharmacology (Berl) . 2021 Jan;238 (1) :215-225.|[3]ocío B Foltran, et al. Neurochemical, Behavioral, and Neurogenic Validation of a Hyposerotonergic Animal Model by Voluntary Oral Consumption of para-Chlorophenylalanine. ACS Chem Neurosci. 2020 Mar 18;11 (6) :952-959.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
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