Trolox (GMP)
Trolox (GMP) is Trolox produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage[1][2].
Product Specifications
CAS Number
53188-07-1
UNSPSC
12352211
Hazard Statement
H315-H319-H401
Target
Apoptosis; Ferroptosis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
O=C(C1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)O
Molecular Formula
C14H18O4
Molecular Weight
250.29
Precautions
P264-P273-P280-P302+P352-P305+P351+P338-P362+P364-P501
References & Citations
[1]Mickle DA, et al. Myocardial salvage with trolox and ascorbic acid for an acute evolving infarction. Ann Thorac Surg. 1989 Apr;47 (4) :553-7.|[2]Forrest VJ, et al. Oxidative stress-induced apoptosis prevented by Trolox. Free Radic Biol Med. 1994 Jun;16 (6) :675-84.|[3]Wu TW, et al. The cytoprotective effect of Trolox demonstrated with three types of human cells. Biochem Cell Biol. 1990 Oct;68 (10) :1189-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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