PAβN (dihydrochloride) (Standard)

PAβN (dihydrochloride) (Standard) is the analytical standard of PAβN (dihydrochloride) (HY-101444A) . This product is intended for research and analytical applications. PAβN dihydrochloride (MC-207110 dihydrochloride) is an efflux pump inhibitor.

Product Specifications

CAS Number

[100929-99-5]

Target

Bacterial; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

O=C([C@H](CCCNC(N)=N)NC([C@H](CC1=CC=CC=C1)N)=O)NC2=CC(C=CC=C3)=C3C=C2.Cl.Cl

Molecular Formula

C25H32Cl2N6O2

Molecular Weight

519.47

References & Citations

[1]Lomovskaya O, et al. Identification and characterization of inhibitors of multidrug resistance efflux pumps in Pseudomonas aeruginosa: novel agents for combination therapy. Antimicrob Agents Chemother. 2001 Jan;45 (1) :105-16.|[2]Kurin?i? M, et al. Effects of efflux pump inhibitors on erythromycin, ciprofloxacin, and tetracycline resistance in Campylobacter spp. isolates. Microb Drug Resist. 2012 Oct;18 (5) :492-501.|[3]Lamers RP, et al. The efflux inhibitor phenylalanine-arginine beta-naphthylamide (PAβN) permeabilizes the outer membrane of gram-negative bacteria. PLoS One. 2013;8 (3) :e60666.