ST-193 (Standard)

ST-193 (Standard) is the analytical standard of ST-193 (HY-101441) . This product is intended for research and analytical applications. ST-193 is a potent broad-spectrum arenavirus inhibitor; inhibits Guanarito, Junin, Lassa and Machupo virus with IC50 values of 0.44, 0.62, 1.4 and 3.1 nM, respectively.

Product Specifications

CAS Number

[489416-12-8]

Target

Arenavirus; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

CC(C1=CC=C(CNC2=CC=C3C(N=CN3C4=CC=C(OC)C=C4)=C2)C=C1)C

Molecular Formula

C24H25N3O

Molecular Weight

371.47

References & Citations

[1]Burgeson JR, et al. Discovery and optimization of potent broad-spectrum arenavirus inhibitors derived from benzimidazole and related heterocycles. Bioorg Med Chem Lett. 2013 Feb 1;23 (3) :750-6.|[2]Larson RA, et al. Identification of a broad-spectrum arenavirus entry inhibitor. J Virol. 2008 Nov;82 (21) :10768-75.|[3]Cashman KA, et al. Evaluation of Lassa antiviral compound ST-193 in a guinea pig model. Antiviral Res. 2011 Apr;90 (1) :70-9.