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Centpropazine

Centpropazine (CNPZ) is a brain-penetrant and non-selective antagonist of serotonin (5-HT1/5-HT2) and adrenergic (α1) receptors. Centpropazine functions by modulating monoamine neurotransmission, particularly reducing serotonin and norepinephrine reuptake, to exert antidepressant effects. Centpropazine is promising for research of depression[1].

Product Specifications

CAS Number

[91315-34-3]

Product Name Alternative

CNPZ

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

5-HT Receptor; Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Neurological Disease

Purity

90.000000

Smiles

CCC(C1=CC=C(OCC(O)CN2CCN(C3=CC=CC=C3)CC2)C=C1)=O

Molecular Formula

C22H28N2O3

Molecular Weight

368.47

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

References & Citations

[1]Bhattaram VA, et al. Evaluation of pharmacokinetics, brain levels and protein binding of centpropazine in rats. Biopharm Drug Dispos. 2004 Mar;25 (2) :69-75.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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