N-Acetylprocainamide (hydrochloride) (Standard)

N-Acetylprocainamide (Acecainide) hydrochloride (Standard) is the analytical standard of N-Acetylprocainamide hydrochloride (HY-101433) . This product is intended for research and analytical applications. N-Acetylprocainamide hydrochloride is a class III antiarrhythmic, which blocks K+ channels. N-Acetylprocainamide hydrochloride exerts inhibitory effects on the maximum following frequency (MFF) of isolated rabbit atria. N-Acetylprocainamide hydrochloride can be used for the study of arrhythmias[1][2][3].

Product Specifications

CAS Number

[34118-92-8]

Product Name Alternative

Acecainide (hydrochloride) (Standard) ; NAPA (hydrochloride) (Standard)

UNSPSC

12352005

Target

Drug Metabolite; Potassium Channel; Reference Standards

Related Pathways

Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease; Others

Field of Research

Cardiovascular Disease

Smiles

O=C(NCCN(CC)CC)C1=CC=C(NC(C)=O)C=C1.Cl

Molecular Formula

C15H24ClN3O2

Molecular Weight

313.82

References & Citations

[1]Nakahara T, et al. Role of K+ channels in N-acetylprocainamide-induced relaxation of bovine tracheal smooth muscle. Eur J Pharmacol. 2001 Mar 9;415 (1) :73-8.|[2]Minchin RF, et al. Antiarrhythmic potency of procainamide and N-acetylprocainamide in rabbits. Eur J Pharmacol. 1978 Jan 1;47 (1) :51-6. |[3]Okumura K, et al. Effects of N-acetylprocainamide on experimental atrial flutter and atrial electrophysiologic properties in conscious dogs with sterile pericarditis: comparison with the effects of quinidine. J Am Coll Cardiol. 1987 Jun;9 (6) :1332-8.