LY-2434074
LY-2434074 is a selective β-secretase (BACE) inhibitor with an IC50 amyloid-β (Aβ40 and Aβ42) production. LY-2434074 can be used for the research of neurological disease, such as Alzheimer's disease[1].
Product Specifications
CAS Number
883446-27-3
UNSPSC
12352005
Target
Amyloid-β; Beta-secretase
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O[C@H]([C@]1([H])N[C@H]([C@@H](OC1)OCC(C)(C)C)C)[C@@H](NC(C)=O)CC2=CC(F)=CC(F)=C2.Cl
Molecular Formula
C21H33ClF2N2O4
Molecular Weight
450.95
References & Citations
[1]Timothy Barrett Durham, et al. 3- (2-acylamino-1-hydroxyethyl) - morpholine derivatives and their use as bace inhibitors. WO2006034093A2. 2006-03-30
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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