GAL-021 (Standard)
GAL-021 (Standard) is the analytical standard of GAL-021. This product is intended for research and analytical applications. GAL-021 is a potent BKCa-channel blocker. GAL-021 inhibits KCa1.1 in GH3 cells. GAL-021 is a novel breathing control modulator that is based on selective modification of the almitrine pharmacophore. GAL-021 increases minute ventilation in rats and non-human primates[1][2].
Product Specifications
CAS Number
1380341-99-0
Target
Potassium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Inflammation/Immunology
Smiles
CCCNC1=NC(N(OC)C)=NC(NCCC)=N1
Molecular Formula
C11H22N6O
Molecular Weight
254.33
References & Citations
[1]Golder FJ, et al. Identification and Characterization of GAL-021 as a Novel Breathing Control Modulator. Anesthesiology. 2015 Nov;123 (5) :1093-104.|[2]J F McLeod, et al. GAL-021, a new intravenous BKCa-channel blocker, is well tolerated and stimulates ventilation in healthy volunteers. Br J Anaesth. 2014 Nov;113 (5) :875-83.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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