ICA-069673 (Standard)
ICA-069673 (Standard) is the analytical standard of ICA-069673. This product is intended for research and analytical applications. ICA-069673 is a KCNQ2/Q3 potassium channel activator. ICA-069673 demonstrates greater selectivity for KV7.2/7.3 over KV7.3/KV7.5, with EC50s of 0.69 μM and 14.3 μM, respectively. ICA-069673 inhibits spontaneous phasic and nerve-evoked contractions in guinea pig detrusor smooth muscle (DSM). ICA-069673 also decreases the global intracellular Ca (2+) concentration in DSM cells[1][2].
Product Specifications
CAS Number
582323-16-8
Target
Potassium Channel; Reference Standards
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
O=C(NC1=CN=C(Cl)N=C1)C2=CC=C(F)C(F)=C2
Molecular Formula
C11H6ClF2N3O
Molecular Weight
269.63
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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