PZM21 (Standard)
PZM21 (Standard) is the analytical standard of PZM21. This product is intended for research and analytical applications. PZM21 is a potent and selective μ opioid receptor agonist with an EC50 of 1.8 nM[1][2][3].
Product Specifications
CAS Number
1997387-43-5
Target
Opioid Receptor; Reference Standards
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Field of Research
Neurological Disease
Smiles
O=C(N[C@@H](C)CC1=CSC=C1)NC[C@@H](N(C)C)CC2=CC=C(O)C=C2
Molecular Formula
C19H27N3O2S
Molecular Weight
361.50
References & Citations
[1]Manglik A, et al. Structure-based discovery of opioid analgesics with reduced side effects. Nature. 2016 Sep 8;537 (7619) :185-190.|[2]Kostic M, et al. Biasing Opioid Receptors and Cholesterol as a Player in Developmental Biology.|[3]Araldi D, et al. Mu-opioid Receptor (MOR) Biased Agonists Induce Biphasic Dose-dependent Hyperalgesia and Analgesia, and Hyperalgesic Priming in the Rat. Neuroscience. 2018 Oct 17;394:60-71.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards
Frequently Asked Questions
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